{"id":11,"date":"2015-11-19T10:26:13","date_gmt":"2015-11-19T10:26:13","guid":{"rendered":"http:\/\/flatsome.dev\/?p=1"},"modified":"2024-04-15T16:56:28","modified_gmt":"2024-04-15T09:56:28","slug":"lap-trinh-lai-adn-ngan-benh-nan-y","status":"publish","type":"post","link":"https:\/\/nexushealth.123websitedev.com\/en\/lap-trinh-lai-adn-ngan-benh-nan-y\/","title":{"rendered":"Reprogramming DNA prevents incurable diseases"},"content":{"rendered":"<p>L\u1ea7n \u0111\u1ea7u ti\u00ean, ADN \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ec3 tr\u1ecb th\u00e0nh c\u00f4ng b\u1ec7nh gan \u1edf chu\u1ed9t. K\u1ef9 thu\u1eadt n\u00e0y c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Down v\u00e0 nh\u1eefng r\u1ed1i lo\u1ea1n di truy\u1ec1n kh\u00e1c trong t\u01b0\u01a1ng lai.<\/p>\n<p>B\u1ec7nh gan do di truy\u1ec1n \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi \u1edf chu\u1ed9t tr\u01b0\u1edfng th\u00e0nh c\u00f2n s\u1ed1ng, trong m\u1ed9t cu\u1ed9c th\u00ed nghi\u1ec7m s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p can thi\u1ec7p gien mang t\u00ednh \u0111\u1ed9t ph\u00e1 trong l\u0129nh v\u1ef1c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh di truy\u1ec1n. K\u1ef9 thu\u1eadt m\u1edbi, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 Crispr, cho ph\u00e9p th\u1ef1c hi\u1ec7n nh\u1eefng \u0111i\u1ec1u ch\u1ec9nh nh\u1ecf nh\u1ea5t tr\u00ean kho d\u1eef li\u1ec7u kh\u1ed5ng l\u1ed3 c\u1ee7a ph\u00e2n t\u1eed ADN v\u1edbi \u0111\u1ed9 ch\u00ednh x\u00e1c ch\u01b0a t\u1eebng c\u00f3 tr\u01b0\u1edbc \u0111\u00e2y. Theo RT, Crispr \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh t\u1eebng \u201cch\u1eef c\u00e1i\u201d trong b\u1ea3n m\u1eabu t\u1ef1 gien c\u1ee7a chu\u1ed9t \u0111\u1ed9t bi\u1ebfn gien c\u00f3 li\u00ean quan \u0111\u1ebfn t\u00ecnh tr\u1ea1ng trao \u0111\u1ed5i ch\u1ea5t b\u1ea5t th\u01b0\u1eddng \u1edf gan. C\u00e1c nh\u00e0 khoa h\u1ecdc cam \u0111oan r\u1eb1ng b\u1ec7nh gan do di truy\u1ec1n \u1edf ng\u01b0\u1eddi c\u0169ng xu\u1ea5t ph\u00e1t t\u1eeb \u0111\u1ed9t bi\u1ebfn t\u01b0\u01a1ng t\u1ef1 nh\u01b0 \u1edf chu\u1ed9t, l\u00e0m d\u1ea5y l\u00ean hy v\u1ecdng c\u00f3 th\u1ec3 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u1edf b\u1ec7nh nh\u00e2n trong v\u00e0i n\u0103m t\u1edbi.<\/p>\n<figure id=\"attachment_219\" aria-describedby=\"caption-attachment-219\" style=\"width: 695px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-219\" src=\"https:\/\/nexushealth.123websitedev.com\/wp-content\/uploads\/2015\/11\/tintuc1-695x400.jpeg\" alt=\"\" width=\"695\" height=\"400\" srcset=\"https:\/\/nexushealth.123websitedev.com\/wp-content\/uploads\/2015\/11\/tintuc1-695x400.jpeg 695w, https:\/\/nexushealth.123websitedev.com\/wp-content\/uploads\/2015\/11\/tintuc1-510x294.jpeg 510w, https:\/\/nexushealth.123websitedev.com\/wp-content\/uploads\/2015\/11\/tintuc1-768x442.jpeg 768w, https:\/\/nexushealth.123websitedev.com\/wp-content\/uploads\/2015\/11\/tintuc1.jpeg 1200w\" sizes=\"auto, (max-width: 695px) 100vw, 695px\" \/><figcaption id=\"caption-attachment-219\" class=\"wp-caption-text\">B\u1ed9 m\u00e3 gen c\u1ee7a con ng\u01b0\u1eddi c\u00f3 r\u1ea5t nhi\u1ec1u gi\u00e1 tr\u1ecb<\/figcaption><\/figure>\n<p>K\u1ebft qu\u1ea3 tr\u00ean l\u00e0 th\u00e0nh t\u1ef1u m\u1edbi nh\u1ea5t trong l\u0129nh v\u1ef1c \u0111i\u1ec1u ch\u1ec9nh gien di truy\u1ec1n v\u00e0 y\u1ebfu t\u1ed1 then ch\u1ed1t ch\u00ednh l\u00e0 Crispr. \u0110\u00e2y l\u00e0 k\u1ef9 thu\u1eadt cho ph\u00e9p gi\u1edbi khoa h\u1ecdc c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n h\u1ea7u h\u1ebft m\u1ecdi \u0111i\u1ec1u ch\u1ec9nh tr\u00ean ADN \u1edf t\u1eebng \u0111i\u1ec3m ch\u00ednh x\u00e1c tr\u00ean nhi\u1ec5m s\u1eafc th\u1ec3 c\u1ee7a \u0111\u1ed9ng v\u1eadt l\u1eabn th\u1ef1c v\u1eadt. Crispr \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o n\u0103m 1987, ban \u0111\u1ea7u b\u1ecb li\u1ec7t v\u00e0o d\u1ea1ng \u201cADN r\u00e1c\u201d nh\u01b0ng sau \u0111\u00f3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 c\u01a1 ch\u1ebf ph\u00f2ng v\u1ec7 \u0111\u01b0\u1ee3c vi khu\u1ea9n s\u1eed d\u1ee5ng \u0111\u1ec3 ch\u1ed1ng s\u1ef1 t\u1ea5n c\u00f4ng c\u1ee7a vi r\u00fat. Tuy nhi\u00ean, ph\u1ea3i \u0111\u1ebfn n\u0103m 2012 &#8211; 2013, gi\u1edbi chuy\u00ean gia m\u1edbi kh\u00e1m ph\u00e1 \u0111\u01b0\u1ee3c ho\u00e0n to\u00e0n n\u0103ng l\u1ef1c \u0111i\u1ec1u ch\u1ec9nh gien th\u1ea7n k\u1ef3 c\u1ee7a k\u1ef9 thu\u1eadt n\u00e0y \u0111\u1ed1i v\u1edbi sinh v\u1eadt b\u1eadc cao, trong \u0111\u00f3 c\u00f3 con ng\u01b0\u1eddi. Li\u1ec7u ph\u00e1p tr\u00ean s\u1eed d\u1ee5ng c\u00e1c enzyme \u201cc\u1eaft\u201d \u0111\u1ec3 can thi\u1ec7p t\u1eebng ph\u1ea7n c\u1ee5 th\u1ec3 tr\u00ean 23 c\u1eb7p nhi\u1ec5m s\u1eafc th\u1ec3 ng\u01b0\u1eddi m\u00e0 kh\u00f4ng g\u00e2y th\u00eam \u0111\u1ed9t bi\u1ebfn b\u1ea5t ng\u1edd.<\/p>\n<p>Trong cu\u1ed9c nghi\u00ean c\u1ee9u m\u1edbi, c\u00e1c nh\u00e0 khoa h\u1ecdc c\u1ee7a Vi\u1ec7n C\u00f4ng ngh\u1ec7 Massachusetts (MIT &#8211; M\u1ef9) \u0111\u00e3 s\u1eed d\u1ee5ng k\u1ef9 thu\u1eadt Crispr \u0111\u1ec3 t\u00ecm ki\u1ebfm v\u00e0 \u0111i\u1ec1u ch\u1ec9nh c\u1eb7p ADN \u0111\u1ed9t bi\u1ebfn tr\u00ean gien gan g\u1ecdi l\u00e0 FAH. \u0110\u1ed9t bi\u1ebfn n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn s\u1ef1 d\u1ed3n \u1ee9 a x\u00edt amino tyrosine nguy hi\u1ec3m trong 1\/100.000 ng\u01b0\u1eddi, khi\u1ebfn b\u1ec7nh nh\u00e2n ph\u1ea3i u\u1ed1ng thu\u1ed1c \u0111\u1eb7c tr\u1ecb v\u00e0 \u00e1p d\u1ee5ng ch\u1ebf \u0111\u1ed9 \u0103n \u00edt protein. Nh\u00f3m chuy\u00ean gia MIT tuy\u00ean b\u1ed1 \u0111\u00e3 ch\u1eefa kh\u1ecfi c\u0103n b\u1ec7nh hi\u1ebfm \u1edf chu\u1ed9t b\u1eb1ng c\u00e1ch thay \u0111\u1ed5i kho\u1ea3ng 1\/3 s\u1ed1 t\u1ebf b\u00e0o gan b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng 3 s\u1ee3i ARN \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh. \u0110\u00e2y l\u00e0 nh\u00f3m ARN \u0111\u00f3ng vai tr\u00f2 l\u00e0m ph\u00e2n t\u1eed \u201cd\u1eabn \u0111\u01b0\u1eddng\u201d \u0111\u1ec3 t\u00ecm \u0111\u01b0\u1ee3c c\u1eb7p gien bi\u1ebfn d\u1ecb, v\u00e0 trong v\u00f2ng 30 ng\u00e0y, c\u00e1c t\u1ebf b\u00e0o kh\u1ecfe m\u1ea1nh b\u1eaft \u0111\u1ea7u \u0111\u01b0\u1ee3c nh\u00e2n l\u00ean thay th\u1ebf t\u1ebf b\u00e0o b\u1ec7nh.<\/p>\n<p>C\u00e1c chuy\u00ean gia MIT cho r\u1eb1ng nh\u1eefng s\u1ef1 can thi\u1ec7p h\u1ebft s\u1ee9c chi ti\u1ebft \u0111\u1ed1i v\u1edbi ADN h\u1ee9a h\u1eb9n c\u00f3 th\u1ec3 cho ph\u00e9p gi\u1edbi khoa h\u1ecdc \u0111i\u1ec1u tr\u1ecb nh\u1eefng r\u1ed1i lo\u1ea1n di truy\u1ec1n nh\u01b0 b\u1ec7nh thi\u1ebfu m\u00e1u h\u1ed3ng c\u1ea7u l\u01b0\u1ee1i li\u1ec1m, h\u1ed9i ch\u1ee9ng Down v\u00e0 b\u1ec7nh Huntington. Kh\u00f4ng nh\u1eefng th\u1ebf, n\u00f3 c\u00f2n c\u00f3 ti\u1ec1m n\u0103ng \u1ee9ng d\u1ee5ng trong l\u0129nh v\u1ef1c li\u1ec7u ph\u00e1p gien, t\u1ee9c thay th\u1ebf gien h\u1ecfng b\u1eb1ng gien kh\u1ecfe m\u1ea1nh tr\u00ean c\u00e1c vi r\u00fat g\u00e2y b\u1ec7nh ch\u01b0a c\u00f3 thu\u1ed1c ch\u1eefa nh\u01b0 HIV\/AIDS v\u00e0 nh\u1eefng c\u0103n b\u1ec7nh ch\u1ebft ng\u01b0\u1eddi nh\u01b0 ung th\u01b0. Th\u1eadm ch\u00ed, c\u00e1c chuy\u00ean gia c\u00f2n cho r\u1eb1ng c\u00f3 th\u1ec3 d\u00f9ng k\u1ef9 thu\u1eadt m\u1edbi \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh nh\u1eefng nh\u01b0\u1ee3c \u0111i\u1ec3m tr\u00ean gien \u1edf ph\u00f4i ng\u01b0\u1eddi \u0111\u01b0\u1ee3c th\u1ee5 tinh trong ph\u00f2ng th\u00ed nghi\u1ec7m, cho ph\u00e9p lo\u1ea1i b\u1ecf c\u00e1c r\u1ed1i lo\u1ea1n di truy\u1ec1n tr\u01b0\u1edbc khi \u0111\u1ee9a tr\u1ebb \u0111\u01b0\u1ee3c th\u1ee5 thai. Tuy nhi\u00ean, m\u1ed9t trong nh\u1eefng tr\u1edf ng\u1ea1i l\u1edbn nh\u1ea5t hi\u1ec7n nay ch\u00ednh l\u00e0 l\u00e0m sao \u00e1p d\u1ee5ng k\u1ef9 thu\u1eadt Crispr an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 cho ng\u01b0\u1eddi.<\/p>\n<p>H\u1ea1o Nhi\u00ean<\/p>","protected":false},"excerpt":{"rendered":"<p>L\u1ea7n \u0111\u1ea7u ti\u00ean, ADN \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ec3 tr\u1ecb th\u00e0nh c\u00f4ng b\u1ec7nh gan \u1edf chu\u1ed9t. K\u1ef9 thu\u1eadt n\u00e0y c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Down v\u00e0 nh\u1eefng r\u1ed1i lo\u1ea1n di truy\u1ec1n kh\u00e1c trong t\u01b0\u01a1ng lai. B\u1ec7nh gan do di truy\u1ec1n \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi \u1edf chu\u1ed9t tr\u01b0\u1edfng th\u00e0nh c\u00f2n s\u1ed1ng, trong [&#8230;]","protected":false},"author":1,"featured_media":219,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-11","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.9 (Yoast SEO v20.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>L\u1eadp tr\u00ecnh l\u1ea1i ADN ng\u0103n b\u1ec7nh nan y - Nexus Health Asia<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L\u1eadp tr\u00ecnh l\u1ea1i ADN ng\u0103n b\u1ec7nh nan y\" \/>\n<meta property=\"og:description\" content=\"L\u1ea7n \u0111\u1ea7u ti\u00ean, ADN \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ec3 tr\u1ecb th\u00e0nh c\u00f4ng b\u1ec7nh gan \u1edf chu\u1ed9t. K\u1ef9 thu\u1eadt n\u00e0y c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Down v\u00e0 nh\u1eefng r\u1ed1i lo\u1ea1n di truy\u1ec1n kh\u00e1c trong t\u01b0\u01a1ng lai. B\u1ec7nh gan do di truy\u1ec1n \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi \u1edf chu\u1ed9t tr\u01b0\u1edfng th\u00e0nh c\u00f2n s\u1ed1ng, trong [...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nexushealth.123websitedev.com\/en\/lap-trinh-lai-adn-ngan-benh-nan-y\/\" \/>\n<meta property=\"og:site_name\" content=\"Nexus Health Asia\" \/>\n<meta property=\"article:published_time\" content=\"2015-11-19T10:26:13+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-15T09:56:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nexushealth.123websitedev.com\/wp-content\/uploads\/2015\/11\/tintuc1.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"691\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nexushealth.123websitedev.com\/lap-trinh-lai-adn-ngan-benh-nan-y\/\",\"url\":\"https:\/\/nexushealth.123websitedev.com\/lap-trinh-lai-adn-ngan-benh-nan-y\/\",\"name\":\"L\u1eadp tr\u00ecnh l\u1ea1i ADN ng\u0103n b\u1ec7nh nan y - Nexus Health Asia\",\"isPartOf\":{\"@id\":\"https:\/\/nexushealth.123websitedev.com\/#website\"},\"datePublished\":\"2015-11-19T10:26:13+00:00\",\"dateModified\":\"2024-04-15T09:56:28+00:00\",\"author\":{\"@id\":\"https:\/\/nexushealth.123websitedev.com\/#\/schema\/person\/b18cc316e057717108548b8efbae5ef9\"},\"breadcrumb\":{\"@id\":\"https:\/\/nexushealth.123websitedev.com\/lap-trinh-lai-adn-ngan-benh-nan-y\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nexushealth.123websitedev.com\/lap-trinh-lai-adn-ngan-benh-nan-y\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nexushealth.123websitedev.com\/lap-trinh-lai-adn-ngan-benh-nan-y\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Trang ch\u1ee7\",\"item\":\"https:\/\/nexushealth.123websitedev.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"L\u1eadp tr\u00ecnh l\u1ea1i ADN ng\u0103n b\u1ec7nh nan y\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nexushealth.123websitedev.com\/#website\",\"url\":\"https:\/\/nexushealth.123websitedev.com\/\",\"name\":\"Nexus Health Asia\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nexushealth.123websitedev.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/nexushealth.123websitedev.com\/#\/schema\/person\/b18cc316e057717108548b8efbae5ef9\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/nexushealth.123websitedev.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ff085648579f958c83522b74afe2ca167bd4ed2d8bb083fd6cbe420aac016d52?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ff085648579f958c83522b74afe2ca167bd4ed2d8bb083fd6cbe420aac016d52?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"sameAs\":[\"https:\/\/nexushealth.123websitedev.com\"],\"url\":\"https:\/\/nexushealth.123websitedev.com\/en\/author\/admin\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"L\u1eadp tr\u00ecnh l\u1ea1i ADN ng\u0103n b\u1ec7nh nan y - Nexus Health Asia","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"L\u1eadp tr\u00ecnh l\u1ea1i ADN ng\u0103n b\u1ec7nh nan y","og_description":"L\u1ea7n \u0111\u1ea7u ti\u00ean, ADN \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ec3 tr\u1ecb th\u00e0nh c\u00f4ng b\u1ec7nh gan \u1edf chu\u1ed9t. K\u1ef9 thu\u1eadt n\u00e0y c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Down v\u00e0 nh\u1eefng r\u1ed1i lo\u1ea1n di truy\u1ec1n kh\u00e1c trong t\u01b0\u01a1ng lai. 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